Online Clinical Case Study (October 2006)

Clinical Cardiology Series
臨床心臟科個案研究

The content of the Office Cardiology Series is provided by:
Dr. LI Siu Lung, Steven
F.H.K.A.M. (Med), F.R.C.P. (Glasg), F.R.C.P. (Edin), F.R.C.P. (Lond), Specialist in
Cardiology

Dr. WONG Shou Pang, Alexander
F.R.C.P., F.H.K.A.M.(Med.), F.H.K.C.P., Specialist in Cardiology

臨床心臟科個案研究之內容誠蒙李少隆醫生王壽鵬醫生提 供。

A 43 year old man was admitted because of sudden palpitation. He enjoyed good past health and has no known coronary risk factors. His blood pressure was 108/56 mmHg.

Answers

1.

His ECG was as followed.

What are your differential diagnoses?

The ECG showed narrow complexes tachycardia at a rate of 173bpm with some ventricular premature beats. The differential diagnoses include atrial flutter and atrioventricular nodal re-entry tachycardia.

 

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2.

ATP 20mg was given IVI as a bolus. This was his ECG strip afterwards. What is your diagnosis?

Underlying flutter waves were seen after the AV block induced by ATP. The diagnosis was atrial flutter.

 

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3. His arrhythmia soon recurred and his blood pressure was now 95/48 mmHg and he complained of some dizziness and chest discomfort. What will you do?
 

In case of hemodynamic instability, DC version is indicated. Atrial flutter usually responds to DC version well and energy as low as 50J may suffice. This was his ECG strip after 50J DC version.

 

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4. What treatment options would be available to prevent future recurrence?
 

Drugs like class III or Ia drugs may prevent further recurrences but they are of considerable side effects and long term maintenance is needed.

Radiofrequency ablation of atrial flutter, on the other hand, achieves a high success rate with a potentially curative effect.

 

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Dermatology Series 皮膚科病例研究

A 56 year old woman noticed multiple asymptomatic whitish spots on her lower limbs for one year. The spots were asymptomatic and they increased in number gradually. There was no history of trauma. Her past health was unremarkable. Physical examination showed multiple well-defined depigmented macules, measuring < 5 mm in diameter. Both lower limbs were affected symmetrically and there were also some lesions on her forearms. She worried about vitiligo.

The content of the Dermatology Series is provided by:
Dr. CHAN Loi Yuen, Dr. KU Lap Shing, Simon & Dr. TANG Yuk Ming, William
Specialist in Dermatology & Venereology

皮膚科病例研究之內容誠蒙陳來源醫生顧立誠醫生鄧旭明醫生提供。

Answers

1.

What is the clinical diagnosis?

The clinical diagnosis is idiopathic guttate hypomelanosis. It is an acquired, benign leukoderma consisting of multiple 2 to 5 mm size white spots found on the shins and forearms. It is a very common condition. It is more common in women and begins around the age of 30 years.

 

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2.

What are the differential diagnoses?

The differential diagnoses are vitiligo, pityriasis versicolor, post-traumatic hypomelanosis and lichen planus.

 

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3.

Did she have vitiligo?

The followings are against the diagnosis of vitiligo: multiple, small lesions of uniform size, and the lesions remain static in size.

 

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4.

What is the cause of this dermatosis?

Skin biopsy demonstrates there is absence of melanin and reduction in number of melanocytes in the lesional area. It is thought to be an inevitable part of ageing process with gradual reduction in melanocyes, a similar process to graying of hair. Sun damage to melanocyte also plays a role.

 

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5.

What is the treatment?

Protection against sunlight is very important. Treatment is not required as the condition is harmless. Topical steroids, topical tretinoin and cryotherapy have been reported to improve the appearance.

 

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